Dr. Prashanth Asuri joined the Bioengineering faculty at Santa Clara University in Fall 2011 after holding research positions in academia and industry. Dr. Asuri earned his Ph.D. in Chemical and Biological Engineering from Rensselaer Polytechnic Institute and M.B.A. with a focus on Leading Innovative Organizations from Santa Clara University. His research efforts focus on the design and development of biomaterial-based in vitro platforms to understand complex in vivo phenomena, and he has published over 50 journal articles, conference proceedings, and book chapters. He teaches undergraduate and graduate courses on topics related to biomaterials, tissue engineering, and healthcare innovation. Dr. Asuri also serves as the Director of the School of Engineering's Healthcare Innovation and Design Program that partners with industry to empower students to discover, innovate, and address complex challenges within healthcare.
Current Research Interests
Our lab interests are interdisciplinary in nature, integrating tools and concepts from biomaterials engineering, nanotechnology, and biology. Our current efforts focus on the development of hydrogel-based models for the assessment of nanoparticle and chemical toxicity, macromolecular crowding and confinement, and the mechanical properties of nanocomposites.
- Introduction to Healthcare Innovation (BIOE 111)
- Biomaterials Science (BIOE 153)
- Introduction to Tissue Engineering (BIOE 172)
- Senior Design Capstone sequence (BIOE 194-196)
- Introduction to Nanobioengineering (BIOE 256)
- Stem Cell Bioengineering (BIOE 269)
- Advanced Topics in Tissue Engineering (BIOE 273)
- Healthcare Marketing (MKTG 3805)
- Droplet microfluidic platform for the determination of single-cell lactate release, Analytical Chemistry, 88, 3257-3263 (2016).
- Three-dimensional matrix stiffness and adhesive ligands affect cancer cell response to toxins, Biotechnology, and Bioengineering, 113, 443-452 (2016).
- Experimental Investigation of mechanical and thermal properties of silica nanoparticle-reinforced poly(acrylamide) nanocomposite hydrogels. PLoS One, 10, e0136293 (2015).
- A novel 2.5D culture platform to investigate the role of stiffness gradients on adhesion-independent cell migration, PLoS One, 9, e110453 (2014).
- Role of three-dimensional matrix stiffness in regulating the response of human neural cells to toxins, Cellular and Molecular Bioengineering, 7, 278-284 (2014).
- Function, structure, and stability of enzymes confined in agarose gels, PLoS One, 9, e86785 (2014).
- Soft microenvironments promote the early neurogenic differentiation but not self-renewal of human pluripotent stem cells, Integrative Biology, 4, 1049-1058 (2012).
- Directed evolution of adeno-associated virus for enhanced gene delivery and gene targeting in human pluripotent stem cells, Molecular Therapy, 20, 329-338 (2012).
- An evolved adeno-associated viral variant enhances gene delivery and gene targeting in neural stem cells, Molecular Therapy, 19, 667-675 (2011).
- Polymer-nanotube-enzyme composites as active antifouling films, Small, 3, 50-53 (2007).
- Protein directed the formation of silver nanoparticles on carbon nanotubes, Advanced Materials, 19, 3167-3170 (2007).
- Nanotube-enzyme conjugates in room temperature ionic liquids, Applied Biochemistry and Biotechnology, 143, 153-164 (2007).
- Directed assembly of carbon nanotubes at liquid-liquid interfaces, Journal of the American Chemical Society, 128, 1046-1047 (2006).
- Increasing protein stability through control of the nanoscale environment, Langmuir, 22, 5833-5836 (2006).